In-Vivo Quantification of Knee Deep-Flexion in Physiological Loading Condition trough Dynamic MRI

The in-vivo quantification of knee motion in physiological loading conditions is paramount for the understanding joint’s natural behavior and comprehension articular disorders. Dynamic MRI (DMRI) represents an emerging technology that makes it possible to investigate functional interaction among all joint tissues without risks patient. However, traditional scanners normally offer a reduced space motion, complex apparatus are needed load articulation, due horizontal orientation scanning bed. In this study, we present experimental computational procedure combines open, weight-bearing scanner with original registration algorithm reconstruct three-dimensional kinematics from DMRI, thus allowing investigation deep-flexion under loads space. To improve accuracy procedure, MR-compatible rig has been developed guide flexion We tested on three volunteers. overall rotational positional achieved 1.8° ± 1.4 1.2 mm 0.8, respectively, they sufficient characterization load.